As fantasy football enthusiasts prepare for Week 10 of the 2025 NFL season, the focus shifts to wide receiver matchups that could significantly influence fantasy outcomes. This analysis highlights players who may exceed or fall short of expectations, rather than the well-established stars like Josh Allen or Ja’Marr Chase.
Top Wide Receiver Picks for Week 10
Among the top recommendations for the week is Puka Nacua, who faces the San Francisco 49ers. Nacua has demonstrated potential and could capitalize on a favorable matchup. Following closely is Jaxon Smith-Njigba, who will take on the Arizona Cardinals. Another player to watch is Amon-Ra St. Brown, set to compete against the Washington Commanders.
The complete list of top ten fantasy wide receivers for Week 10 includes:
1. Puka Nacua at 49ers
2. Jaxon Smith-Njigba vs. Cardinals
3. Amon-Ra St. Brown at Commanders
4. Drake London at Colts (Berlin)
5. Justin Jefferson vs. Ravens
6. Davante Adams at 49ers
7. Nico Collins vs. Jaguars
8. A.J. Brown at Packers (Monday)
9. Michael Pittman Jr. vs. Falcons (Berlin)
10. Emeka Egbuka vs. Patriots
Byes this week include teams such as the Cincinnati Bengals, Kansas City Chiefs, and Dallas Cowboys.
Start Recommendations
Several wide receivers are primed for strong performances this week. Rome Odunze is expected to rebound against the New York Giants after a disappointing showing last week. The Giants’ pass defense has allowed the seventh-most points per game to wide receivers, which could provide Odunze the opportunity to shine.
Another player worth considering is Tetairoa McMillan, who faces the New Orleans Saints. Despite a lackluster performance last week, he has the potential to excel against a defense that has allowed significant points to perimeter receivers this season.
Additionally, Devonta Smith has shown consistent performance with over 14 points in three of his last four games. His upcoming match against the Green Bay Packers looks promising, as their defense ranks among the worst in terms of points allowed to wide receivers.
Further, Quentin Johnston is emerging as a solid option against the Pittsburgh Steelers, who have struggled against perimeter receivers this season. Johnston’s recent performance indicates he can capitalize on this matchup.
Finally, Wan’Dale Robinson is poised to take advantage of the Chicago Bears defense, which has allowed the third-most points per game to slot receivers.
Players to Sit This Week
Conversely, some players should be approached with caution this week. DK Metcalf faces a tough matchup against the Los Angeles Chargers, who have limited perimeter receivers to just one touchdown this season. Despite his star status, managing expectations is key.
Another player to consider sitting is Brian Thomas Jr., who continues to struggle, having scored only 8.5 points last week. His matchup against the Houston Texans, one of the stingiest defenses for receivers, adds to the concern.
Chris Olave may also be a risky start against the Carolina Panthers, who have allowed minimal points to opposing wideouts. With limited targets last week, Olave’s production is uncertain.
Additionally, Jordan Addison faces the Ravens after a disappointing outing against the Detroit Lions. With the uncertainty surrounding the quarterback position, caution is advised.
Lastly, Deebo Samuel Sr. has struggled to find the end zone recently, making him a potential sit against the Lions, despite their weak defense on paper.
As Week 10 approaches, these insights may help fantasy football players make informed decisions about their lineups. Keeping an eye on player performances and matchups can make all the difference in a competitive fantasy league.
